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A new research paper titled "Cell type-dependent modulation of senescence features using Weo electrolyzed water" has been published in Aging . Electrolyzed-reduced water has powerful antioxidant properties with constituents that scavenge reactive oxygen species (ROS), which are known to be produced by several intrinsic and extrinsic processes. When there is an imbalance between ROS production and antioxidant defenses, oxidative stress occurs.

Persistent oxidative stress leads to cellular senescence , an important hallmark of aging, and is involved in several age-related conditions and illnesses. In this new study, researchers Brenda L. Court-Vazquez, Shirley A.



Arroyo-Vizcarrondo, Jonathan A. Poli, Lara Nyman, Kelly Halderman, Anthony Ginter, and Pierre-Yves Desprez from Weo LLC and California Pacific Medical Center investigated whether Weo electrolyzed water (WEW) could modulate the phenotype of senescent cells. "The focus of this study was to utilize two different cell types, human normal fibroblasts and human breast cancer cells , to investigate the impact of Weo electrolyzed water (WEW) on markers of cellular senescence, inflammation, and stress response genes," the researchers explain.

The researchers compared normal human lung fibroblasts (BJ) and breast cancer cells (T47D) treated with hydrogen peroxide (H 2 O 2 ) to induce senescence. They assessed the molecular impact of WEW on markers of cellular senescence, senescence-associated secretory phenotype (SASP) factors, .

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