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July 12, 2024 This article has been reviewed according to Science X's editorial process and policies . Editors have highlightedthe following attributes while ensuring the content's credibility: fact-checked trusted source proofread by Samantha Martin, University of York A new technology aims to take gene therapies a step further, making it possible for the treatment to be used more widely, at lower cost, and with improved outcomes for patients. Dr.

Rasha Rezk and Professor David Kent, from the Center for Blood Research at the University of York, have created the technology, which uses mechanical forces to help deliver gene modifying tools to the body's cells. They are now scaling up the technology for clinical application through their new company, ForCell. The new technology can open a cell through compression, in a similar way to how a French press plunger operates.



This action temporarily opens the cell to deliver genetic information without damaging or altering the cell, as is the risk with current methods. Currently, the majority of gene therapy is administered by removing some cells from the body and correcting the genetic material using virus-based tools, before returning the cells to the patient. Such therapies already exist for a wide range of genetic disorders such as sickle cell disease and severe combined immunodeficiency (SCID) where genetic corrections can restore cell function.

Scientists use viruses as part of gene therapy methods because a virus has the abili.

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