Newswise — Despite its revered status in traditional Chinese medicine, Saposhnikovia divaricata has not been thoroughly studied genetically. This herb, used to treat rheumatism and skin conditions, holds untapped potential due to unknown genetic and metabolic profiles. The recent study aims to fill this gap by mapping its genome, offering insights that could improve its medicinal properties through advanced breeding and biotechnological methods, potentially leading to superior therapeutic applications.
Published (DOI: 10.1093/hr/uhae105) in April 2024 in Horticulture Research , this collaborative research involved Jilin Agricultural University and various other institutions, including international partners from the University of British Columbia. Leveraging cutting-edge sequencing technologies, the study delivers a chromosome-level genome assembly, providing a deeper understanding of the plant’s intricate genetic structure and its adaptation strategies.
The genomic analysis of Saposhnikovia divaricata uncovered a genome size of 2.07 Gb, rich in repetitive sequences and marked by a notable whole-genome duplication. These characteristics indicate a vast genetic diversity and adaptability, essential for its survival and medicinal effectiveness.
The study pinpointed several gene families crucial for synthesizing key pharmacological agents like flavonoids and plant hormones. Furthermore, comparative genomic studies with related species illuminate unique evolutionary paths and.