Since revealing she was diagnosed with multiple sclerosis (MS) in 2021, Christina Applegate has been candid about her health and how's she's doing. Most recently, she shared in the which she co-hosts with Jamie-Lynn Sigler, that she is "in a depression right now, which I don't think I've felt for years." for over 20 years.

"Like a real, f--k it all, like real depression, where it’s kind of scaring me too a little bit because it feels really fatalistic," Applegate continued. "I’m trapped in this darkness right now that I haven’t felt like — I don’t even know how long, probably 20 something years. .

.. I don’t enjoy living.

I don’t enjoy things anymore." The three-year anniversary of Applegate's diagnosis is approaching, but she's still struggling with accepting it, she said: "I can’t believe it’s going to be three years since my diagnosis in June. And I’m still sitting here like, ‘Boohoo, woe is me.

’ I’m still mad about it." "I’m kind of just like giving up," she explained. "I’m so like, ‘Well, this is it.

' I’m just going to lay in bed and sleep all the time, and then when my daughter needs me, I’ll be there for her and I’ll do everything for her." The "Dead To Me" star initially in August 2021. MS is a “potentially disabling disease of the brain and spinal cord,” .

MS can create “communication problems between your brain and the rest of your body” and “permanent damage or deterioration of the nerve fibers.” Read on for a full t.