Christina Applegate has been left in a deep "depression" because of her MS. The former Married With Children star - who was diagnosed with the neurological condition in 2021 - confessed that she is in a really "fatalastic, f**k it" headspace with her mental health after coming to terms with living the symptoms like mobility issues, fatigue and bowel control. The 52-year-old actress told her friend and actress Jamie-Lynn Sigler on their podcast 'MeSsy': "I'm in a depression right now, which I don't think I've felt that for years.

Like a real, f**k it all depression where it's kind of scaring me a little bit because it feels really fatalistic. "I'm trapped in like this darkness right now that I haven't felt like..

. I don't even know how long, probably 20 something years." Journalism for the curious Australian across politics, business, culture and opinion.

Applegate also mentioned her surprise presenting stint at this year's Primetime Emmy Awards with pal Anthony Anderson, 53, as support. She told her 43-year-old pal - who also has MS - that the gig was part of "the hardest day of [her] life" and that she slept for "two days" after. While being frank about her condition, Applegate said: "This is being really honest.

..I don't enjoy living.

I don't enjoy it. I don't enjoy things anymore." Sigler - who is best known for playing Tony Soprano's daughter Meadow on the legendary HBO series The Sopranos - admitted that she knew how hard it can be but found it easier to not live in the .