, /PRNewswire/ -- The iConquerMSTM People-Powered Research Network (PPRN) ( ), a research initiative of the Accelerated Cure Project (ACP), is partnering with the Department of Veterans Affairs (VA), the digital therapy company , Charité – Universitatsmedizin Berlin, the University Medical Center Göttingen, and Ordinal Data, Inc., on a four-year, large-scale clinical trial of online programs, or digital therapeutics, for treating fatigue in multiple sclerosis (MS). This trial is funded by a nearly grant from the Department of Defense (DoD) Congressionally Directed Medical Research Programs (CDMRP), Multiple Sclerosis Research Program (MSRP).
For many people living with MS, fatigue is a common symptom that limits their ability to engage in regular everyday activities. Affecting about 70 percent of people with MS (PwMS), it accounts for a substantial portion of the disability and psychosocial burden of this disease. While medication-based treatments have had mixed results in studies and carry risks of side effects, analyses of a number of smaller studies show treatment with non-pharmacological approaches may be effective and safe.
The clinical trial will assess the effectiveness of two online programs and will be conducted with the goal of gaining FDA approval of a novel, non-pharmacological therapy for fatigue in MS. Although they differ, both of these online programs contain potentially useful information about MS and fatigue intended to help PwMS understand and manage .