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The bird flu outbreak in U.S. dairy cows is prompting development of new, next-generation mRNA — akin to COVID-19 shots — that are being tested in both animals and people.

Next month, the U.S. Agriculture Department is to begin testing a vaccine developed by University of Pennsylvania researchers by giving it to calves.



The idea: If vaccinating cows protects dairy workers, that could mean fewer chances for the virus to jump into people and mutate in ways that could spur human-to-human spread. Meanwhile. the U.

S. Department of Health and Human Services has been talking to manufacturers about possible mRNA flu vaccines for people that, if needed, could supplement millions of bird flu vaccine doses already in government hands. “If there's a pandemic, there's going to be a huge demand for vaccine,” said Richard Webby, a flu researcher at St.

Jude Children’s Research Hospital in Memphis. “The more different (vaccine manufacturing) platforms that can respond to that, the better." The bird flu virus has been spreading among more animal species in scores of countries since 2020.

It was detected in U.S. dairy herds in March, although investigators think it may have been in cows since December.

This week, the USDA announced it had been found in alpacas for the first time. At least three people — all workers at farms with infected cows — have been diagnosed with bird flu, although the illnesses were considered mild. But earlier versions of the same H5N1 flu virus have be.

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