CDC Personalized flu jabs are a major step nearer following a significant breakthrough. Researchers have developed a way of classifying an individual person’s ability to resist infection - known as host immunity - which they say will make vaccine programs more effective. They believe the discovery may lead to the early identification of those who will not respond well to a regular vaccine schedule - and therefore allow them to receive different vaccine doses to provide them with long-lasting immunity.
It will not only reduce flu-related illness but also slash the logistical and financial burden it causes to healthcare systems, say scientists. Influenza causes serious illness in three to five million people worldwide each year and 650,000 deaths,. The effectiveness of flu vaccines varies considerably between individuals depending on vaccine types and individual circumstances.
A person’s ability to resist infection plays an important role, say scientists. Ed Us Dr. Nhan Nguyen and his colleagues took blood samples from 286 healthy donors aged 18 to 81 during four flu seasons to try to identify those who would be unprotected against influenza after vaccination.
Dr. Nguyen said: “After examining their pre- and post-vaccination antibody status, we used multiomics technology to identify proteins and metabolites that could serve as predictive markers for the identification of individuals who have low levels of protection even after vaccination. “This is a more sophisticated .
