A recent study published in JAAC CardioOncology reviewed preclinical and epidemiologic evidence linking air pollution to cardio-oncology. Study: Air Pollution in Cardio-Oncology and Unraveling the Environmental Nexus: JACC: CardioOncology State-of-the-Art Review . Image Credit: Inside Creative House/Shutterstock.
com Cancer therapies have substantially improved the survival rate of patients. However, chronic health conditions have emerged as the lifespan of cancer patients increased. Cardio-oncology refers to the research and clinical practice of predicting, preventing, and treating cardiotoxicity due to cancer therapy.
Over time, cardio-oncology has expanded and includes multifaceted and bidirectional links between cancer and cardiovascular disease (CVD). Air pollution has emerged as an environmental risk factor for cancer and CVD. Air pollution has been implicated in oxidative stress, immune response, and metabolic remodeling, which may amplify the effects of risk factors.
Although air pollution is a recognized risk factor for CVD and cancer, its role within cardio-oncology has received little attention. The present study reviewed the evidence linking cancer and CVD, emphasizing the effects of air pollution on cardio-oncology. Exposure to particulate matter ≤ 2.
5 (PM 2.5 ) has been associated with atherosclerosis, hypertension, stroke, and heart attack. Air pollution is also associated with cancer, especially lung cancer.
The Global Burden of Disease study revealed that PM.
