A study investigated predictive models for cognitive decline in early Alzheimer’s patients, examining the impact of new drugs that target amyloid-beta plaques. Researchers developed models comparing predicted declines in cognitive test scores with actual outcomes, observing both the accuracy of these predictions and the potential delay in decline due to drug treatments. Credit: SciTechDaily.
com A 2024 study assesses predictive models for Alzheimer’s -related cognitive decline and evaluates new drugs’ effectiveness in slowing this decline. A new study looks at predicting how quickly people with early Alzheimer’s disease will experience cognitive decline. The study is published in the July 10, 2024, online issue of Neurology , the medical journal of the American Academy of Neurology.
It also looked at how the new drugs recently approved for the disease may reduce decline. “The rate of cognitive decline varies greatly from person to person, and people are very interested in what to expect from the disease in themselves or their loved ones, so better prediction models are urgently needed,” said study author Pieter J. van der Veere, M.
D., of Amsterdam University Medical Center, Netherlands. Study Details and Cognitive Assessment The researchers developed models to predict how quickly people’s scores would decline on a test of thinking and memory skills.
Then they compared the models to actual results from people over time. They studied 961 people with an average age .
