A new study by Penn researchers examined, for the first time, the differences in lung transplant graft outcomes from organs recovered from the two types of deceased organ donor care facilities operating in the United States. The research, published today in JAMA Network Open , offers insights that could improve the organ donation and transplantation process for patients across the nation. In the U.
S., deceased organ donors are traditionally cared for in hospitals, which provide intensive care and testing needed to rehabilitate organs, identify transplant recipients, and perform organ recovery surgeries. Over the past two decades, some donors have been transferred from hospitals to donor care units (DCUs), which provide similar services but focus solely on deceased donors.
Two types of DCUs currently operate in the US: independent – located outside of acute-care hospitals- and hospital-based. Researchers analyzed lung donation rates and lung transplant survival outcomes from almost eleven thousand deceased donors who underwent organ recovery procedures between April 2017 and June 2022. The researchers hypothesized that lung transplant survival would not significantly differ between organs recovered from donors managed in these two types of units.
However, the study showed that while independent donor centers generally saw higher donation rates, recipients of lungs from hospital-based DCUs had longer survival. These insights could drive improvements in organ donor management .
