In a recent study published in the journal BMC Medicine , researchers conducted a randomized controlled trial (RCT) to investigate whether short-term interventions combining alcohol-metabolizing enzyme substances, alcohol dehydrogenase 1B (ADH1B) and aldehyde dehydrogenase 2 (ALDH2), with behavioral alterations in alcohol consumption could lower excessive alcohol intake. Study: Effectiveness of genetic feedback on alcohol metabolism to reduce alcohol consumption in young adults: an open-label randomized controlled trial . Image Credit: Guayo Fuentes / Shutterstock Excessive alcohol intake can cause health problems such as acute alcohol poisoning, risky conduct, injury, rape, and suicide.
Young adulthood is a high-risk phase for alcohol misuse, and excessive consumption can lead to alcohol use problems later in life. Public health initiatives should aim to reduce high-risk alcohol intake among young individuals. Brief interventions, such as counseling sessions, have been tested to raise awareness about alcohol consumption and its repercussions.
Studies demonstrate that intervention recipients' average daily alcohol intake significantly reduced six months later. Understanding an individual's alcohol-metabolizing enzyme genotype and following preventative practices can assist in solving alcohol-related health issues. In the present open-label RCT, researchers investigated the influence of short ADH1B and ALDH2 gene polymorphism screening treatments on alcohol intake among Japane.
