Newswise — Polyfluoroalkyl substances (PFAS) are a class of chemicals extensively used in consumer goods production due to their hydrophobic and oleophobic properties and stability. However, their persistence in the environment and bioaccumulation in living organisms have sparked concerns about potential health effects. Previous studies have linked PFAS exposure to various adverse outcomes, including developmental issues in children.
A recent study (DOI:10.1016/j.eehl.
2024.04.007) published in Eco-Environment & Health on May 8, 2024, has highlighted the levels, health risks, and transport protein binding capabilities of per- and polyfluoroalkyl substances (PFAS) in early life based on the Shanghai Maternal-Child Pairs Cohort.
Found in maternal serum, cord serum, and breast milk, these synthetic chemicals pose potential health risks for infants. Led by research team from School of Public Health at Fudan University, the research team meticulously analyzed the transfer mechanisms and impacts of these persistent chemicals, providing crucial insights into their pervasive presence from pregnancy to lactation. Employing high-performance liquid chromatography-tandem mass spectrometry, the study analyzed 16 types of PFAS in 1,076 mother-child pairs.
It revealed the detection rates and median concentrations of perfluorooctane sulfonate (PFOS), perfluorooctanoic acid (PFOA), and 6:2 Cl-PFESA, with PFOS most prevalent in maternal serum. Notably, placental transfer efficiency of PFAS wa.
